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World’s Oldest Toothpaste Recipe Found in Egypt Reveals Ancient Greek Dental Secrets

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A variety of ingredients, including herbs, coarse salt, and peppercorns, are arranged on a rustic wooden table alongside a mortar and pestle for making ancient-style toothpaste.
The natural, abrasive components used by Ancient Greeks to maintain oral hygiene, such as crushed oyster shells, charcoal, and mint. Credit: Greek Reporter archive

Most of us assume that looking after our teeth is a modern habit shaped by supermarket shelves, mint-flavored ads, and childhood dentist scares, but a surviving Ancient Greek toothpaste recipe suggests otherwise.

Sitting quietly in the Austrian National Library in Vienna is one of the most remarkable documents in the history of medicine: a small, faded papyrus from the fourth century AD containing what is widely considered the world’s oldest surviving, precise toothpaste formula.

The existence of this Ancient Greek toothpaste recipe points to something larger at work. By the time it was copied onto papyrus, Greek had long since become the language of science, medicine, and intellectual life across the Mediterranean. This linguistic dominance was a legacy of the conquests of Alexander the Great and, above all, of Alexandria, the city his successors transformed into the ancient world’s foremost hub of knowledge. Even in Roman Egypt, centuries after the Ptolemies had given way to the Caesars, Greek remained the language a physician used when he wanted to be taken seriously.

When was the toothpaste recipe written in Ancient Greek discovered?

The papyrus first came to the attention of modern researchers in 2003, when curators at the Austrian National Library in Vienna identified it while preparing for an international dental congress. It had likely been sitting in the collection for years, its significance unnoticed and largely forgotten. Once translated, however, scholars quickly realized what they were looking at—a toothpaste formula that predates the first commercially marketed toothpaste, Colgate, launched in 1873, by well over fifteen hundred years.

The formula itself is strikingly systematic. The scribe prescribes “a powder for white and perfect teeth” composed of four ingredients: one drachma of rock salt, two drachmas of mint, one drachma of dried iris flower, and twenty grains of pepper. The drachma in this context was a standard unit of Greek medical weight, roughly equivalent to one-eighth of an ounce (about 3–4 grams), part of the same measurement system used throughout the major pharmacological texts of the ancient world. Taken together, the recipe reads less like folklore and more like a physician’s deliberate prescription, carefully calibrated for a patient.

But one might wonder if it actually worked. In 2003, Austrian dentist Dr. Heinz Neuman decided to test it for himself by recreating the formula. His conclusion was cautious but intriguing: the mixture was mildly abrasive and caused slight gum bleeding, yet it also produced a noticeable sensation of cleanliness and freshness. Modern dental science helps explain why. Dried iris flower, or orris root, is now known to contain antibacterial compounds that target the pathogens responsible for gum disease. What might once have looked like ancient guesswork increasingly appears to be empirical knowledge derived through observation and practice. In this sense, modern pharmaceutical science is only now arriving at conclusions the Greeks and Egyptians had already explored more than a thousand years earlier.

Ancient Greek father of pharmacology
Dioscorides is considered the father of pharmacology. Painting of unknown artist depicting Heuresis (the personification of discovery) presenting Dioscorides with a mandrake root. Credit: Unknown artist. Wikipedia Public Domain

None of this should entirely surprise us when we consider the world from which this recipe emerged. Ancient Greece had produced Pedanius Dioscorides, whose monumental work on medicinal plants shaped medical practice for more than a millennium. It had also produced physicians, botanists, and scholars who approached the human body with a level of rigor and curiosity that few ancient traditions matched. The anonymous scribe who recorded this formula was working squarely within that intellectual lineage, effectively encoding practical medical knowledge in Greek because it was the language in which serious medicine was conducted at the time.

The paste itself would have been applied without anything resembling a modern toothbrush. A folded linen cloth or a frayed chew stick—a fibrous twig worn soft at the tip through repeated use—would have served the purpose well enough. The tools were simple, but the intention was essentially the same as ours.

There is a quiet continuity in that detail. The next time you reach for mint toothpaste in the morning, you are participating in a ritual that a Greek-speaking scribe in Roman Egypt thought important enough to preserve on papyrus seventeen centuries ago. The ingredients have been refined, the packaging has changed beyond recognition, and no one is applying the mixture with linen anymore. Still, the impulse behind it—the very human desire for clean, white teeth—remains as old as the ancient world itself, and in many ways, the Ancient Greek world had already put the first working version of the answer into writing.

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