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China Creates “Bone Glue” that Heals Fractures in Minutes

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A newly discovered bone glue inspired by oysters heals fractures quickly and could reduce the need for surgery. Credit: wikimedia commons / Frankie Fouganthin CC-BY-4.0

Chinese researchers have developed a “bone glue” designed to heal fractures in minutes, potentially transforming how broken bones are treated in emergency settings.

The injectable material, called Bone-02, mimics how oysters and similar marine animals form strong bonds in wet environments — enabling it to stick to living bone even in the presence of blood and bodily fluids.

The bone glue, which forms a stable hold within minutes of application, could eliminate the need for complex surgical procedures in certain cases. Scientists say the material not only bonds quickly but also supports natural bone regeneration. Over time, it is absorbed by the body as new bone tissue forms.

Inspired by marine life for use in medicine

Prime Media Plus, a media outlet that reported on the breakthrough, described Bone-02 as a nature-inspired solution modeled on how shell-forming species adhere to underwater surfaces.

The developers adapted those biological mechanisms to work inside the human body, where traditional adhesives often fail due to moisture and movement.

Unlike conventional bone cements such as polymethyl methacrylate, which provide mechanical support but do not chemically bond to bone or break down over time, Bone-02 forms a direct interface with bone tissue. It gradually degrades as the healing bone strengthens, potentially reducing the need for permanent implants.

In early testing, the adhesive has shown strong bonding performance in wet conditions and appears to integrate progressively with bone. Researchers say these qualities could offer major clinical benefits, particularly in trauma care, where fast stabilization is critical.

The material could also reduce reliance on metal plates, screws, or external devices, especially in treating vertebral compression fractures and injuries involving small bone fragments.

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