The feature is being likened to “Meet the Parents” and “What About Bob?,” reports Variety.
The film, which began shooting earlier this week in Oregon, is produced by “Saturday Night Live” creator Lorne Michaels and directed by Matt Villines and Osmany Rodriguez.
Other cast members include Bill Pullman, Rachael Harris, David Wain and “SNL” stars Taran Killam and Bobby Moynihan.
No word on what role Wilson will play in the comedy.
The Greek-American actress recently wrapped production on “Kiss Me” and will also be featured in the films “Dawn Patrol” and “Facing the Wind.”